Tag: amyloid fibrils

  • Primary Amyloidosis

    Primary Amyloidosis: Definition and Description of Primary Amyloidosis: Primary amyloidosis, also known as AL amyloidosis, is a rare disease that occurs when abnormal proteins, known as light chains, misfold and aggregate into fibrils. These fibrils deposit in various tissues and organs, disrupting normal function. The condition is often associated with an underlying plasma cell disorder…

  • Prealbumin Tyr-77 Amyloidosis

    Prealbumin Tyr-77 Amyloidosis: Definition and Description of Prealbumin Tyr-77 Amyloidosis: Prealbumin Tyr-77 Amyloidosis is a rare form of systemic amyloidosis characterized by the misfolding and aggregation of the prealbumin protein (also known as transthyretin) at the Tyr-77 amino acid position. This condition results in the deposition of amyloid fibrils in various tissues and organs, leading…

  • Isoleucine 33 Amyloidosis

    Isoleucine 33 Amyloidosis Definition and Description of Isoleucine 33 Amyloidosis Isoleucine 33 Amyloidosis is a rare form of systemic amyloidosis, characterized by the abnormal accumulation of amyloid fibrils derived from the protein Isoleucine-33 (I33). This protein misfolding leads to the deposition of amyloid proteins in various organs, severely disrupting normal function. Amyloidosis can affect the…