Tag: bone marrow disorders

  • Refractory Anemia

    Refractory Anemia: Definition and Description of Refractory Anemia: Refractory anemia is a subtype of anemia, characterized by the body’s failure to produce an adequate amount of red blood cells. It is a chronic condition often associated with ineffective hematopoiesis, which means that the production of blood cells in the bone marrow is not functioning properly.…

  • Paroxysmal Nocturnal Hemoglobinuria (PNH)

    Paroxysmal Nocturnal Hemoglobinuria (PNH): Definition and Description of Paroxysmal Nocturnal Hemoglobinuria (PNH): Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare, acquired bone marrow disorder characterized by the destruction of red blood cells (hemolysis), which leads to the release of hemoglobin into the urine. This condition occurs due to a mutation in the PIGA gene, resulting in…