Tag: bone marrow transplant

  • Mucopolysaccharidosis Type II

    Mucopolysaccharidosis Type II: Definition and Description of Mucopolysaccharidosis Type II: Mucopolysaccharidosis Type II (MPS II), also known as Hunter syndrome, is a rare genetic disorder that falls under the category of lysosomal storage diseases. It is caused by a deficiency of the enzyme iduronate-2-sulfatase (I2S), which plays a crucial role in breaking down glycosaminoglycans (GAGs).…

  • Mucopolysaccharidoses

    Mucopolysaccharidoses: Definition and Description of Mucopolysaccharidoses: Mucopolysaccharidoses (MPS) are a group of inherited lysosomal storage disorders caused by the deficiency of specific enzymes necessary to break down glycosaminoglycans (GAGs), which are long chains of sugar molecules. These enzymes play a vital role in metabolism, and their deficiency leads to the accumulation of GAGs in various…

  • GVHD

    GVHD Definition and Description of GVHD Graft-versus-host disease (GVHD) is a medical condition that occurs when donor immune cells attack the recipient’s body following a transplant procedure, particularly after a stem cell or bone marrow transplant. The donor cells recognize the recipient’s tissues as foreign, leading to an immune response. There are two main types…

  • Chronic Myeloid Leukemia

    Chronic Myeloid Leukemia Definition and Description of Chronic Myeloid Leukemia Chronic Myeloid Leukemia (CML) is a type of cancer that originates in the blood-forming cells of the bone marrow and leads to the overproduction of myeloid cells, which are a category of white blood cells. CML is often characterized by the presence of the Philadelphia…