Tag: motor dysfunction

  • Subcortical Ischemic Vascular Disease

    Subcortical Ischemic Vascular Disease: Definition and Description of Subcortical Ischemic Vascular Disease: Subcortical Ischemic Vascular Disease (SIVD) is a neurological condition characterized by damage to the deep white matter of the brain caused by reduced blood flow, often linked to small vessel disease. It primarily affects the subcortical structures, including the basal ganglia and thalamus,…

  • Huntington’s Chorea (HD)

    Huntington’s Chorea (HD) Definition and Description of Huntington’s Chorea (HD) Huntington’s Chorea, also known as Huntington’s Disease (HD), is a hereditary neurodegenerative disorder characterized by progressive motor dysfunction, cognitive decline, and psychiatric symptoms. This condition is caused by a genetic mutation in the HTT gene, which leads to the production of an abnormal form of…

  • HD

    HD Definition and Description of HD Huntington’s Disease (HD) is a progressive neurodegenerative disorder characterized by motor dysfunction, cognitive decline, and emotional disturbances. It typically emerges between the ages of 30 and 50, although symptoms can manifest at any age. Medical definitions describe HD as an autosomal dominant disorder caused by a genetic mutation in…

  • Galactocerebroside Beta-Galactosidase Deficiency

    Galactocerebroside Beta-Galactosidase Deficiency Galactocerebroside Beta-Galactosidase Deficiency Definition and Description of Galactocerebroside Beta-Galactosidase Deficiency Galactocerebroside Beta-Galactosidase Deficiency, also known as Krabbe disease, is a rare genetic disorder that primarily affects the nervous system. This condition is characterized by the deficiency of the enzyme galactocerebrosidase (GALC), responsible for breaking down galactolipids in the myelin sheath. Without this…

  • Fibrinoid Leukodystrophy

    Fibrinoid Leukodystrophy Definition and Description of Fibrinoid Leukodystrophy Fibrinoid Leukodystrophy is a rare neurological disorder characterized by the degeneration of white matter in the brain. This condition is associated with the accumulation of fibrinoid material that disrupts normal brain function. It primarily affects the myelin sheath, which is essential for the proper conduction of electrical…