Tag: organ dysfunction

  • Lysosomal Storage Disorders

    Lysosomal Storage Disorders Definition and Description of Lysosomal Storage Disorders Lysosomal Storage Disorders (LSDs) are a group of inherited metabolic conditions that result in the malfunction of lysosomes, which are cellular organelles responsible for breaking down waste materials and cellular debris. When lysosomes do not function properly, harmful substances can accumulate in cells, leading to…

  • Icelandic Type Amyloidosis (Type VI)

    Icelandic Type Amyloidosis (Type VI) Definition and Description of Icelandic Type Amyloidosis (Type VI) Icelandic Type Amyloidosis, also known as Type VI amyloidosis, is a rare form of systemic amyloidosis characterized by the deposition of amyloid fibrils primarily composed of mutated transthyretin (TTR) protein. This condition primarily affects individuals of Icelandic descent, due to a…

  • Illinois Type Amyloidosis

    Illinois Type Amyloidosis Definition and Description of Illinois Type Amyloidosis Illinois Type Amyloidosis, a subset of systemic amyloidosis, is characterized by the deposition of amyloid protein in various tissues and organs, leading to dysfunction. This condition primarily affects the circulation and can significantly impair organ function, particularly the kidneys, heart, and nervous system. Causes of…